GPH

ENGINEERING RESEARCH

Cardiac Systems Biology Group

University of Virginia

Top engineering lab at UVA using AI and ML to find new treatments for heart failure

Undergraduate Researcher (PI: Jeffery Saucerman, Ph.D. ↗)
October 2022 – Present | Charlottesville, VA

Lampe Biomaterials Group

Undergraduate Researcher (PI: Kyle Lampe, Ph.D. ↗)
August 2022 – August 2024 | Charlottesville, Virginia
Peptide Synthesis Hydrogel Synthesis Cell Culture Rheometry Fiji [ImageJ] Microscopy
  • Synthesized and optimized 5 distinct peptide hydrogels, including KYFIL, under varying experimental conditions to mimic brain tissue stiffness for targeted treatments, such as stroke.
  • Cultured oligodendrocyte progenitor cells under sterile conditions to evaluate cell viability within the synthesized hydrogels.
  • Conducted rheological testing using an oscillatory rheometer to quantify hydrogel viscoelasticity and tune mechanical properties to match native brain ECM.
  • Performed image-based morphological analyses to validate hydrogel structure, porosity, and consistency across formulations using microscopy techniques.

Merryman Mechanobiology Laboratory

Vanderbilt University
June 2023 – August 2023 | Nashville, TN
Western Blot qPCR Mouse Dissection
  • Contributed to parallel studies on heart valve disease: one on serotonin's role in mitral regurgitation, the other on siRNA therapies targeting cadherin-11 in aortic stenosis.
  • Performed Western blot, qPCR, and mouse anatomical dissection to investigate molecular mechanisms of valvular diseases, gaining practical insights into potential therapeutic targets.
  • Presented research findings in a symposium to faculty, professionals, and students.